In scleroderma, the skin and blood vessels typically become thickened and hard, and people may have swelling or pain in their muscles and joints.

CREST syndrome is a form of systemic sclerosis (SSc), a condition that causes the hardening and tightening of the skin. Other names for this condition are cutaneous systemic sclerosis or limited scleroderma.

The outlook for those with SSc and CREST syndrome is improving. The 10-year survival rate for CREST syndrome, which has slow and late organ involvement, is over 90%.

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Treatment options vary depending on the severity of the symptoms. However, doctors may prescribe anti-inflammatory and immunosuppressant drugs.

Experts are unsure of the exact cause of scleroderma and CREST syndrome. However, it appears to be an autoimmune condition. This means that the immune system attacks the body’s connective tissue.

Scleroderma is a rare, autoimmune condition in which the body produces too much collagen, causing the skin and connective tissue to thicken.

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However, those with more severe or systemic symptoms may require ongoing monitoring. Severe forms of SSc also have a higher mortality rate because of the effects on the heart and lungs.

CREST syndrome is an autoimmune condition that affects the connective tissues. The word CREST is an acronym for the conditions five main features.

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The localized type only affects the skin, whereas the systemic type affects the skin and other body parts. These might include underlying tissues, blood vessels, and major organs, such as the heart, lungs, and kidneys.

People should work with their doctor for individualized treatment plans to control their symptoms. Surgery may sometimes be needed to reduce organ damage or improve blood flow.

However, people with SSc have an increased risk of malignancies, especially lung cancer. This means that regular checkups are necessary.

Telangiectasias are small widened blood vessels near the surface of the skin. They typically present only a visual issue.

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The outlook for those with CREST syndrome is improving due to advances in treatment, and people can often lead normal lives. However, regular checkups are still beneficial because of the increased risk of malignancies.

It can cause symptoms such as Raynaud’s phenomenon, swelling and stiffness in the joints, thickening and hardening of the skin, difficulty swallowing, and other symptoms.

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Although CREST follows the same process as typical scleroderma, organ involvement comes slower and later in the disease course.

CREST syndrome affects various systems in the body, and the symptoms a person experiences can depend on the affected organ. Doctors use a variety of tests to diagnose CREST syndrome.

CREST syndrome is a type of scleroderma that is slow to progress. Scleroderma refers to a group of diseases affecting the connective tissue that supports the skin and organs.

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